I am now running the big cat on my MacPro in the office and running into some different issues. Only one real problem, my keychain went bellyup. Not sure why, since my issue did not meet the criteria of the Keychain update that Apple released this weekend.
One software update that I had not noticed but is necessary for those running the Logitech Cordless Desktop® S 530 Laser for Mac® is to their Control Center. It is up to 2.3.1 and can be downloaded from here. (I actually only use the mouse now, preferring the new Apple slim keyboard for typing.)